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PER1 [cytosol]
Stable Identifier
r - hsa - 400373
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Period circadian protein homolog 1, PER1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Circadian Clock (Homo sapiens)
BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins (Homo sapiens)
Beta-TrCP1:PER [cytosol] (Homo sapiens)
PER1,PER2 [cytosol] (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
Beta-TrCP1 binds phosphorylated PER proteins (Homo sapiens)
Beta-TrCP1:PER [cytosol] (Homo sapiens)
PER1,PER2 [cytosol] (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)
CRY:PER:Kinase [cytosol] (Homo sapiens)
PER1,PER2 [cytosol] (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
Expression of PERIOD-1 (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
Formation of CRY:PER:Kinase complex (Homo sapiens)
CRY:PER:Kinase [cytosol] (Homo sapiens)
PER1,PER2 [cytosol] (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
PER1,PER2 [cytosol] (Homo sapiens)
PER1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15534 PER1
Gene Names
PER1, KIAA0482, PER, RIGUI
Chain
chain:1-1290
Reference Genes
BioGPS Gene:5187 PER1
COSMIC (genes):PER1 PER1
CTD Gene:5187 PER1
dbSNP Gene:5187 PER1
ENSEMBL:ENSG00000179094 PER1
HGNC:8845 PER1
KEGG Gene (Homo sapiens):5187 PER1
Monarch:5187 PER1
NCBI Gene:5187 PER1
OMIM:602260 PER1
UCSC:O15534 PER1
Reference Transcript
RefSeq:XM_005256689.1 PER1
RefSeq:NM_002616.2 PER1
Other Identifiers
0003360735
11717168_a_at
11747289_a_at
11760378_at
16840846
202861_at
242832_at
36829_at
3744151
3744152
3744153
3744156
3744158
3744159
3744160
3744163
3744164
3744165
3744166
3744167
3744168
3744169
3744170
3744171
3744172
3744175
3744176
3744177
3744178
3744179
3744181
3744182
3744183
3744185
3744187
3744189
3744192
3744195
3744197
3744198
3744199
3744200
3744201
3744202
3744203
3744208
3744213
43608_at
5187
8012349
A_23_P89589
A_24_P93916
GE81168
GO:0000122
GO:0000976
GO:0000978
GO:0001222
GO:0002028
GO:0003674
GO:0003677
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006412
GO:0006464
GO:0006810
GO:0006950
GO:0007165
GO:0007623
GO:0008134
GO:0008150
GO:0009058
GO:0009416
GO:0009649
GO:0010608
去:0019899
GO:0019900
GO:0031490
GO:0031625
GO:0032922
GO:0034641
GO:0042634
GO:0042752
GO:0043124
GO:0043153
GO:0043226
GO:0043966
GO:0043967
GO:0045892
GO:0045944
GO:0046329
去:0048511
GO:0051276
GO:0051591
GO:0070888
GO:0070932
GO:0097167
: 1900015
: 1900744
GO:2000323
HMNXSV003009693
Hs.193762.0.A1_3p_at
ILMN_1653125
PH_hs_0026050
TC17002849.hg
g4505712_3p_s_at
Participates
as an output of
Expression of PERIOD-1 (Homo sapiens)
as a member of
PER1,PER2 [cytosol] (Homo sapiens)
Other forms of this molecule
p-S-PER1 [cytosol]
p-S-PER1 [nucleoplasm]
Ub-p-S-PER1 [cytosol]
Cross References
RefSeq
XP_005256746.1
,
NP_002607.2
OpenTargets
ENSG00000179094
HPA
ENSG00000179094-PER1
GeneCards
O15534
Ensembl
ENST00000317276
,
ENSP00000314420
,
ENSP00000346979
,
ENST00000354903
,
ENSG00000179094
PRO
O15534
Pharos - Targets
O15534
PDB
1UL6
Interactors (34)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49674 CSNK1E
2
CSNK1E [nucleoplasm]
(R-HSA-421306)
CSNK1E [cytosol]
(R-HSA-205877)
0.725
4
UniProt:P97784 Cry1
4
Cry1 [cytosol]
(R-MMU-508637)
ub-p-Cry1 [nucleoplasm]
(R-MMU-517961)
p-Cry1 [nucleoplasm]
(R-MMU-508662)
p-Cry1 [cytosol]
(R-MMU-508644)
0.564
3
UniProt:O75460-2 ERN1
0.556
3
UniProt:P22607 FGFR3
40
FGFR3 K650N [plasma membrane]
(R-HSA-1614406)
FGFR3 K650T [plasma membrane]
(R-HSA-1614411)
FGFR3 K650M [plasma membrane]
(R-HSA-1614402)
FGFR3 K650Q [plasma membrane]
(R-HSA-1614410)
FGFR3 A391E [plasma membrane]
(R-HSA-1614390)
FGFR3 K650E [plasma membrane]
(R-HSA-1614400)
FGFR3 G380R [plasma membrane]
(R-HSA-1614398)
FGFR3 G382D [plasma membrane]
(r - hsa - 2018740)
FGFR3 795fs*139 [plasma membrane]
(R-HSA-1614387)
FGFR3 [plasma membrane]
(R-HSA-2038357)
FGFR3 S371C [plasma membrane]
(R-HSA-1614421)
FGFR3 Y373C [plasma membrane]
(r - hsa - 1614424)
FGFR3 G370C [plasma membrane]
(R-HSA-1614394)
FGFR3 R248C [plasma membrane]
(R-HSA-1614419)
p-6Y-FGFR3 S371C [plasma membrane]
(R-HSA-2011886)
p-6Y-FGFR3 G370C [plasma membrane]
(R-HSA-2011883)
p-6Y-FGFR3 Y373C [plasma membrane]
(R-HSA-2011889)
p-6Y-FGFR3 795fs*139 [plasma membrane]
(R-HSA-2038360)
p-6Y-FGFR3 R248C [plasma membrane]
(R-HSA-2011884)
pY-FGFR3 [plasma membrane]
(R-HSA-2038368)
p-6Y-FGFR3 K650Q [plasma membrane]
(R-HSA-2032962)
p-6Y-FGFR3 K650N [plasma membrane]
(R-HSA-2032961)
p-6Y-FGFR3 K650E [plasma membrane]
(R-HSA-2032952)
p-6Y-FGFR3 K650M [plasma membrane]
(R-HSA-2032959)
p-6Y-FGFR3 G380R [plasma membrane]
(R-HSA-2032946)
p-6Y-FGFR3 G382D [plasma membrane]
(R-HSA-2032950)
p-6Y-FGFR3 K650T [plasma membrane]
(R-HSA-2032966)
p-6Y-FGFR3 A391E [plasma membrane]
(R-HSA-2065835)
p-4Y FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]
(R-HSA-8853147)
p-4Y FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
(R-HSA-8853155)
p-4Y FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
(R-HSA-8853145)
tacc p-4Y FGFR3 (23 - 758)3(549-838) fusion [plasma membrane]
(R-HSA-8853129)
tacc p-4Y FGFR3 (23 - 758)3(649-838) fusion [plasma membrane]
(R-HSA-8853151)
p-4Y FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]
(R-HSA-8853128)
FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]
(R-HSA-8853144)
FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]
(R-HSA-8853131)
FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
(R-HSA-8853152)
FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]
(R-HSA-8853124)
FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane]
(R-HSA-8853125)
FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
(R-HSA-8853127)
0.556
3
UniProt:Q99832 CCT7
1
CCT7 [cytosol]
(R-HSA-390451)
0.556
3
UniProt:P49591 SARS1
1
SARS [cytosol]
(R-HSA-379691)
0.556
3
UniProt:P60201-2 PLP1
0.556
3
UniProt:O75400-2 PRPF40A
0.556
3
UniProt:P41091 EIF2S3
1
EIF2S3 [cytosol]
(R-HSA-72514)
0.556
3
UniProt:P62826 RAN
2
RAN [cytosol]
(R-HSA-165540)
RAN [nucleoplasm]
(R-HSA-165528)
0.556
3
UniProt:O60333-2 KIF1B
0.556
3
UniProt:O60356 NUPR1
0.556
3
UniProt:P54652 HSPA2
2
HSPA2 [cytosol]
(R-HSA-3371408)
HSPA2 [nucleoplasm]
(R-HSA-912480)
0.556
3
UniProt:P29692-2 EEF1D
0.556
3
UniProt:Q8WXH2 JPH3
0.556
3
UniProt:Q0VDC6 Q0VDC6
0.556
3
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:P60891 PRPS1
1
PRPS1 [cytosol]
(R-HSA-73483)
0.556
3
UniProt:Q8WUW1 BRK1
1
BRK1 [cytosol]
(R-HSA-1671645)
0.556
3
UniProt:Q9P1I4 Q9P1I4
0.556
3
UniProt:P28799 GRN
2
GRN [extracellular region]
(R-HSA-6806217)
GRN [azurophil granule lumen]
(R-HSA-6799168)
0.556
3
UniProt:P04792 HSPB1
3
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
HSPB1 [cytosol]
(R-HSA-450563)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:P06396 GSN
7
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN(200-270) [extracellular region]
(r - hsa - 976940)
GSN [extracellular region]
(R-HSA-6806510)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN [cytosol]
(R-HSA-350275)
0.556
3
UniProt:P14136 GFAP
3
GFAP [lysosomal membrane]
(R-HSA-9625195)
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:P55212 CASP6
5
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:O76024 WFS1
3
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:Q14957 GRIN2C
3
p-Y-GRIN2C [plasma membrane]
(R-HSA-9612189)
GRIN2C [plasma membrane]
(R-HSA-419560)
GRIN2C [endoplasmic reticulum membrane]
(R-HSA-9609761)
0.556
3
UniProt:Q92870-2 Q928702
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:P07237 P4HB
3
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:P46379-2 BAG6
0.556
3
UniProt:P01112 HRAS
23
HRAS Q61L [plasma membrane]
(R-HSA-6802452)
HRAS Q61R [plasma membrane]
(R-HSA-6802458)
HRAS Q61K [plasma membrane]
(R-HSA-6802442)
HRAS G13R [plasma membrane]
(R-HSA-6802368)
HRAS G12V [plasma membrane]
(R-HSA-6802350)
HRAS G12S [plasma membrane]
(R-HSA-6802343)
HRAS T58I [plasma membrane]
(R-HSA-9656014)
HRAS G13C [plasma membrane]
(R-HSA-9656008)
HRAS K117R [plasma membrane]
(r - hsa - 9656010)
HRAS G13V [plasma membrane]
(R-HSA-9656579)
HRAS G13D [plasma membrane]
(R-HSA-9656572)
HRAS G13S [plasma membrane]
(R-HSA-9656574)
HRAS K117N [plasma membrane]
(R-HSA-9656603)
HRAS G12D [plasma membrane]
(R-HSA-9656564)
HRAS G12C [plasma membrane]
(R-HSA-9656561)
HRAS [plasma membrane]
(R-HSA-62717)
proHRAS [cytosol]
(R-HSA-9647765)
S-Farn-proHRAS [endoplasmic reticulum membrane]
(R-HSA-9647918)
S-Farn-HRAS [endoplasmic reticulum membrane]
(R-HSA-9647788)
S-Farn-Me HRAS [endoplasmic reticulum membrane]
(R-HSA-9647796)
S-Farn-Me PalmS HRAS [Golgi membrane]
(R-HSA-9647896)
S-Farn-Me HRAS [plasma membrane]
(R-HSA-9665052)
S-Farn-Me-2xPalmS HRAS [plasma membrane]
(R-HSA-9647912)
0.556
3
UniProt:Q9R194 Cry2
4
Cry2 [cytosol]
(R-MMU-508614)
ub-p-Cry2 [nucleoplasm]
(R-MMU-517964)
p-Cry2 [nucleoplasm]
(R-MMU-508638)
p-Cry2 [cytosol]
(R-MMU-508666)
0.499
3
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