Reactome | 2xHP-HIF1A [cytosol]

2 xhp-hif1a(胞质)

稳定的标识符

r - hsa - 1234131

类型

蛋白质(EntityWithAccessionedSequence)

物种

智人

室

胞质

同义词

HIF1A含羟脯氨酸402和-564，缺氧诱导因子1- α， HIF1A_HUMAN

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外部参考信息

外部引用

UniProt: Q16665 HIF1A

基因名字

Hif1a, bhlhe78, mop1, pasd8

链

链:1 - 826

参考基因

BioGPS基因:3091 HIF1A

宇宙(基因):HIF1A HIF1A

CTD基因:3091 HIF1A

dbSNP基因:3091 HIF1A

运用:ENSG00000100644 HIF1A

HGNC: 4910 HIF1A

KEGG基因(智人):3091 HIF1A

君主:3091 HIF1A

NCBI基因:3091 HIF1A

人类:603348 HIF1A

UCSC: Q16665 HIF1A

参考文本

其他标识符

0001770044

0002760180

1039年_s_at

11718757 _s_at

11718758 _a_at

11718759 _x_at

11747800 _a_at

11749123 _a_at

11749648 _a_at

11749649 _x_at

11755737 _x_at

16785058

200989 _at

3091

3539073

3539074

3539075

3539083

3539084

3539085

3539087

3539088

3539089

3539090

3539091

3539093

3539094

3539095

3539097

3539098

3539099

3539100

3539102

3539103

3539104

3539105

75276 _at

7974851

A_14_P117087

A_24_P56388

A_33_P3231277

GE59057

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HMNXSV003055761

ILMN_1681283

ILMN_1763260

ILMN_2379788

PH_hs_0028366

TC14002197.hg

U22431_s_at

g4504384_3p_at

参与

作为输出

HIF1A上的胞质PHD2,3个羟化脯氨酸残基(智人)

作为

羟亲hif - α[细胞溶胶](智人)

这个分子的其他形式

2 xhp-hif1a(核浆)

HN-HIF1A(胞质)

p-Y565, S797-HIF1A(胞质)

p-Y565-HIF1A(胞质)

HIF1A(胞质)

HIF1A(核浆)

推断,

硅镁层(胞质)(黑腹果蝇)

HIF1A(胞质)(犬属后裔)

HIF1A(胞质)(背带背带)

HIF1A(胞质)(野猪)

Hif1a(胞质)(亩骶)

Hif1a(胞质)(鼠形)

hif-1(胞质)(线虫)

hif1a(胞质)(非洲爪蟾蜍tropicalis)

hif1ab(胞质)(鲐鱼类)

修改后的残留物

的名字

单羟基脯氨酸在402

协调

402

PsiMod名字

monohydroxylated脯氨酸

PsiMod定义

一种蛋白质修饰，能有效地将l -脯氨酸残基转化为几种单羟基脯氨酸残基之一，包括3-羟基- l -脯氨酸和4-羟基- l -脯氨酸。

的名字

单羟基脯氨酸在564

协调

564

PsiMod名字

monohydroxylated脯氨酸

PsiMod定义

一种蛋白质修饰，能有效地将l -脯氨酸残基转化为几种单羟基脯氨酸残基之一，包括3-羟基- l -脯氨酸和4-羟基- l -脯氨酸。

交叉引用

RefSeq

NP_001230013.1，NP_001521.1，NP_851397.1

锌-世界药品

HIF1A_HUMAN

OpenTargets

ENSG00000100644

锌- FDA批准

HIF1A_HUMAN

锌-物质

HIF1A_HUMAN

锌-生物

HIF1A_HUMAN

锌的目标

Q16665

箴

Q16665

PDB

4 ajy，5成为jwp，1 h2l，1 h2m，1 l8c，1 l3e，5 l9v，6 gfx，5 la9，4 h6j，3 hqr，1 lm8，2 ilm，5拉斯维加斯，6 gmr，3 hqu，1 h2k，1 lqb，6 yw3，1 d7g，5 l9b

锌-代谢物

HIF1A_HUMAN

下丘脑-垂体-肾上腺轴的

ENSG00000100644-HIF1A

GeneCards

Q16665

运用

ENST00000323441，ENSG00000100644，ENST00000337138，ENST00000539097，ENSP00000338018，ENSP00000323326，ENSP00000437955

灯塔,目标

Q16665

锌-预测-可购买

HIF1A_HUMAN

Orphanet

24596

扶少团团员(42)

加入	#实体	实体	信心得分	证据(完整)
UniProt: Q09472 EP300	5	Foxo4-S-S-EP300(核浆)(r - hsa - 9617720) 1024 - ep300 SUMO1-K1020(核浆)(r - hsa - 3899306) FOXO4-S-S-EP300(核浆)(r - hsa - 9617691) p-S, T-EP300(核浆)(r - hsa - 8878072) EP300(核浆)(r - hsa - 381325)	0.962	20.
UniProt: P40337 VHL	3.	VHL(核浆)(r - hsa - 1234127) SUMO1-K159,171,196-VHL(核浆)(r - hsa - 4551697) VHL(胞质)(r - hsa - 391423)	0.957	20.
UniProt: P27540 ARNT	1	ARNT(核浆)(r - hsa - 1234098)	0.929	12
UniProt: Q9NWT6 HIF1AN	1	HIF1AN(胞质)(r - hsa - 1234154)	0.922	12
UniProt: Q9H6Z9 EGLN3	2	EGLN3(核浆)(r - hsa - 1234104) EGLN3(胞质)(r - hsa - 1234115)	0.881	7
UniProt: Q9GZT9 EGLN1	1	EGLN1(胞质)(r - hsa - 1234108)	0.803	5
UniProt: Q15370 ELOB	2	TCEB2(核浆)(r - hsa - 112423) ELOB(胞质)(r - hsa - 180551)	0.789	8
完整:ebi - 2895491 VEGFA			0.725	6
UniProt: Q15369 ELOC	2	TCEB1(核浆)(r - hsa - 112422) ELOC(胞质)(r - hsa - 180535)	0.702	5
UniProt: P63165 SUMO1	155	TOPORS-G97-SUMO1(核浆)(r - hsa - 4551623) K14-UBE2I-G97-SUMO1(核浆)(r - hsa - 4085334) PIAS4-G97-SUMO1(核浆)(r - hsa - 3968375) K2592-RANBP2-G97-SUMO1(核被膜)(r - hsa - 4551627) K2723-RANBP2-G97-SUMO1(核被膜)(r - hsa - 4551737) K2650-RANBP2-G97-SUMO1(核被膜)(r - hsa - 4551591) K196-VHL-G97-SUMO1(核浆)(r - hsa - 4551630) K171-VHL-G97-SUMO1(核浆)(r - hsa - 4551632) K159-VHL-G97-SUMO1(核浆)(r - hsa - 4551713) MDM-G97-SUMO1(核浆)(r - hsa - 3730829) K575-TRIM28-G97-SUMO1(核浆)(r - hsa - 4090305) K804-TRIM28-G97-SUMO1(核浆)(r - hsa - 3782561) K750-TRIM28-G97-SUMO1(核浆)(r - hsa - 4090298) K676-TRIM28-G97-SUMO1(核浆)(r - hsa - 4090396) K554-TRIM28-G97-SUMO1(核浆)(r - hsa - 3782555) K779-TRIM28-G97-SUMO1(核浆)(r - hsa - 3782585) ING2-G97-SUMO1(核浆)(r - hsa - 4086096) K788-Ncoa2-G97-SUMO1(核浆)(r - hsa - 4085297) K731-Ncoa2-G97-SUMO1(核浆)(r - hsa - 4085312) K239-Ncoa2-G97-SUMO1(核浆)(r - hsa - 4085320) K239-NCOA2-G97-SUMO1(核浆)(r - hsa - 4085299) K731-NCOA2-G97-SUMO1(核浆)(r - hsa - 4085290) K788-NCOA2-G97-SUMO1(核浆)(r - hsa - 4085308) NPM1-G97-SUMO1(核浆)(r - hsa - 4086019) NCOR2-G97-SUMO1(核浆)(r - hsa - 3927883) DDX17-G97-SUMO1(核浆)(r - hsa - 3900210) PARK7-G97-SUMO1(核浆)(r - hsa - 4085344) K1033-CREBBP-G97-SUMO1(核浆)(r - hsa - 3927910) K1056-CREBBP-G97-SUMO1(核浆)(r - hsa - 3927954) K998-CREBBP-G97-SUMO1(核浆)(r - hsa - 3927822) K1154-NRIP1-G97-SUMO1(核浆)(r - hsa - 4086067) K756-NRIP1-G97-SUMO1(核浆)(r - hsa - 4086034) DDX5-G97-SUMO1(核浆)(r - hsa - 3900212) CASP8AP2-G97-SUMO1(核浆)(r - hsa - 3927863) K1024-EP300-G97-SUMO1(核浆)(r - hsa - 3899298) K1020-EP300-G97-SUMO1(核浆)(r - hsa - 3899290) CTBP1-G97-SUMO1(核浆)(r - hsa - 3730764) K231-SAFB-G97-SUMO1(核浆)(r - hsa - 4085364) K294-SAFB-G97-SUMO1(核浆)(r - hsa - 4085341) K624-MKL1-G97-SUMO1(核浆)(r - hsa - 3900128) K576-MKL1-G97-SUMO1(核浆)(r - hsa - 3900225) K499-MKL1-G97-SUMO1(核浆)(r - hsa - 3900219) K631-DAXX-G97-SUMO1(核浆)(r - hsa - 4086044) K630-DAXX-G97-SUMO1(核浆)(r - hsa - 4086012) SIN3A-G97-SUMO1(核浆)(r - hsa - 4086058) PPARGC1A-G97-SUMO1(核浆)(r - hsa - 3903014) HIPK2-G97-SUMO1(核浆)(r - hsa - 4090362) K774-NCOA1-G97-SUMO1(核浆)(r - hsa - 4085292) K732-NCOA1-G97-SUMO1(核浆)(r - hsa - 4085278) K538-MBD1-G97-SUMO1(核浆)(r - hsa - 4090416) K499-MBD1-G97-SUMO1(核浆)(r - hsa - 4090332) ZNF131-G97-SUMO1(核浆)(r - hsa - 3730875) K90-NFKB2-G97-SUMO1(胞质)(r - hsa - 4755511) K689-NFKB2-G97-SUMO1(胞质)(r - hsa - 4755446) K863-NFKB2-G97-SUMO1(胞质)(r - hsa - 4755412) K298-NFKB2-G97-SUMO1(胞质)(r - hsa - 4755505) p-S172-IKBKE-G97-SUMO1(核浆)(r - hsa - 4755408) K309-IKBKG-G97-SUMO1(核浆)(r - hsa - 4755404) K277-IKBKG-G97-SUMO1(核浆)(r - hsa - 4755531) NFKBIA-G97-SUMO1(核浆)(r - hsa - 4656987) AURKA-G97-SUMO1(胞质)(r - hsa - 4655413) TOP2B-G97-SUMO1(核浆)(r - hsa - 4641311) TOP1-G97-SUMO1(核浆)(r - hsa - 4641306) TOP2A-G97-SUMO1(核浆)(r - hsa - 4641341) K254-PCNA-G97-SUMO1(核浆)(r - hsa - 4615853) K-PCNA-G97-SUMO1(核浆)(r - hsa - 4615836) K164-PCNA-G97-SUMO1(核浆)(r - hsa - 4615951) MDC1-G97-SUMO1(核浆)(r - hsa - 4570527) STAG2-G97-SUMO1(核浆)(r - hsa - 3826645) RAD21-G97-SUMO1(核浆)(r - hsa - 3826574) K411-RAD52-G97-SUMO1(核浆)(r - hsa - 4568857) K412-RAD52-G97-SUMO1(核浆)(r - hsa - 4568850) K414-RAD52-G97-SUMO1(核浆)(r - hsa - 4568900) XRCC4-G97-SUMO1(核浆)(r - hsa - 4568869) K160-PML-G97-SUMO1(核浆)(r - hsa - 3730884) K490-PML-G97-SUMO1(核浆)(r - hsa - 3730833) K65-PML-G97-SUMO1(核浆)(r - hsa - 3730879) K203-PARP1-G97-SUMO1(核浆)(r - hsa - 4551625) K486-PARP1-G97-SUMO1(核浆)(r - hsa - 4551748) K496-WRN-G97-SUMO1(核浆)(r - hsa - 4568906) K898-WRN-G97-SUMO1(核浆)(r - hsa - 4568893) K356-WRN-G97-SUMO1(核浆)(r - hsa - 4568845) RNF168-SUMO1(核浆)(r - hsa - 4551631) XPC-G97-SUMO1(核浆)(r - hsa - 4570452) TDG-G97-SUMO1(核浆)(r - hsa - 4551682) SP100-G97-SUMO1(核浆)(r - hsa - 3730794) BRCA1-G97-SUMO1(核浆)(r - hsa - 3730735) RXRA-G97-SUMO1(核浆)(r - hsa - 4341090) NR5A2-G97-SUMO1(核浆)(r - hsa - 4755424) K386-AR-G97-SUMO1(核浆)(r - hsa - 4090321) K520-AR-G97-SUMO1(核浆)(r - hsa - 4090352) K293-NR3C1-G97-SUMO1(核浆)(r - hsa - 4341110) K277-NR3C1-G97-SUMO1(核浆)(r - hsa - 4341057) K389-THRA-G97-SUMO1(核浆)(r - hsa - 4719415) K283-THRA-G97-SUMO1(核浆)(r - hsa - 4719434) K399-NR3C2-G97-SUMO1(核浆)(r - hsa - 4341020) K428-NR3C2-G97-SUMO1(核浆)(r - hsa - 4341035) K494-NR3C2-G97-SUMO1(核浆)(r - hsa - 4341093) K89-NR3C2-G97-SUMO1(核浆)(r - hsa - 4341058) K119-NR5A1-G97-SUMO1(核浆)(r - hsa - 4546379) K194-NR5A1-G97-SUMO1(核浆)(r - hsa - 4546380) NR2C1-G97-SUMO1(核浆)(r - hsa - 4717492) K303-ESR1-G97-SUMO1(核浆)(r - hsa - 4090373) K266-ESR1-G97-SUMO1(核浆)(r - hsa - 4090359) K302-ESR1-G97-SUMO1(核浆)(r - hsa - 4090363) K299-ESR1-G97-SUMO1(核浆)(r - hsa - 4090349) K268-ESR1-G97-SUMO1(核浆)(r - hsa - 4090414) K531-PGR-G97-SUMO1(核浆)(r - hsa - 4341021) K7-PGR-G97-SUMO1(核浆)(r - hsa - 4341052) K388-PGR-G97-SUMO1(核浆)(r - hsa - 4341056) K132-NR1H4-G97-SUMO1(核浆)(r - hsa - 9610527) NR1H4-G97-SUMO1(核浆)(r - hsa - 4755434) PPARG-G97-SUMO1(核浆)(r - hsa - 4717445) K395-PPARG-G97-SUMO1(核浆)(r - hsa - 4717446) PPARA-G97-SUMO1(核浆)(r - hsa - 4341069) K443-THRB-G97-SUMO1(核浆)(r - hsa - 4719431) K146-THRB-G97-SUMO1(核浆)(r - hsa - 4719410) K50-THRB-G97-SUMO1(核浆)(r - hsa - 4719401) RORA-G97-SUMO1(核浆)(r - hsa - 4719426) HIC1-G97-SUMO1(核浆)(r - hsa - 4570544) TP53BP1-G97-SUMO1(核浆)(r - hsa - 3730731) SP3-G97-SUMO1(核浆)(r - hsa - 3730646) K423-MITF-G97-SUMO1(核浆)(r - hsa - 3730755) K289-MITF-G97-SUMO1(核浆)(r - hsa - 3730738) K25-FOXL2-G97-SUMO1(核浆)(r - hsa - 3968400) K150-FOXL2-G97-SUMO1(核浆)(r - hsa - 3968382) K114-FOXL2-G97-SUMO1(核浆)(r - hsa - 3968396) HNRNPC-G97-SUMO1(核浆)(r - hsa - 4570515) K497-NOP58-G97-SUMO1(核浆)(r - hsa - 4570504) K467-NOP58-G97-SUMO1(核浆)(r - hsa - 4570462) DNMT3B-G97-SUMO1(核浆)(r - hsa - 4655444) DNMT3A-G97-SUMO1(核浆)(r - hsa - 4655383) DNMT1-G97-SUMO1(核浆)(r - hsa - 4655358) K84-CBX5-G97-SUMO1(核浆)(r - hsa - 4615838) K-CBX5-G97-SUMO1(核浆)(r - hsa - 4615955) K476-HDAC1-G97-SUMO1(核浆)(r - hsa - 4615867) K444-HDAC1-G97-SUMO1(核浆)(r - hsa - 4616028) CBX4-G97-SUMO1(核浆)(r - hsa - 4551756) HDAC2-G97-SUMO1(核浆)(r - hsa - 4616032) SUZ12-G97-SUMO1(核浆)(r - hsa - 4615961) SATB1-G97-SUMO1(核浆)(r - hsa - 4615877) HDAC4-G97-SUMO1(核浆)(r - hsa - 4615956) K1971-CHD3-G97-SUMO1(核浆)(r - hsa - 8956370) HIST1H4-G97-SUMO1(核浆)(r - hsa - 4570549) BMI1-G97-SUMO1(核浆)(r - hsa - 4551654) TFAP2B-G97-SUMO1(核浆)(r - hsa - 3730839) TFAP2C-G97-SUMO1(核浆)(r - hsa - 3730823) TFAP2A-1-G97-SUMO1(核浆)(r - hsa - 3730825) UBE2I-G97-SUMO1(胞质)(r - hsa - 4656941) RANGAP1-G97-SUMO1(核浆)(r - hsa - 3730796) SUMO1(2 - 101)(核浆)(r - hsa - 2990831) SUMO1(核浆)(r - hsa - 877304) UBA2-G97-SUMO1(核浆)(r - hsa - 3730616) UBE2I-G97-SUMO1(核浆)(r - hsa - 3730622) HERC2-SUMO1(核浆)(r - hsa - 4551761)	0.688	4
UniProt: Q96KS0 EGLN2	1	EGLN2(核浆)(r - hsa - 1234117)	0.683	3.
UniProt: O00257 CBX4	2	CBX4(核浆)(r - hsa - 389118) SUMO1-K494-CBX4(核浆)(r - hsa - 4551626)	0.674	15
UniProt: P41227 NAA10			0.667	3.
UniProt: P40337-3 VHL			0.659	6
UniProt: Q13438 OS9	1	OS9[内质网膜](r - hsa - 1022132)	0.649	9
UniProt: Q92793 CREBBP	3.	FOXO4-S-S-CREBBP(核浆)(r - hsa - 9617684) SUMO1-K998、K1033 K1056-CREBBP(核浆)(r - hsa - 3927877) CREBBP(核浆)(r - hsa - 193545)	0.609	2
UniProt: P09467 FBP1	1	FBP1(胞质)(r - hsa - 70476)	0.602	5
UniProt: P14618-1 PKM	1	PKM-1(胞质)(r - hsa - 71667)	0.591	7
UniProt: P17861 XBP1			0.591	3.
UniProt: P11474 ESRRA	1	ESRRA(核浆)(r - hsa - 446159)	0.576	3.
UniProt: P25789 PSMA4	2	PSMA4(胞质)(r - hsa - 68730) PSMA4(核浆)(r - hsa - 174324)	0.576	4
UniProt: Q16665 HIF1A	7	2 xhp-hif1a(核浆)(r - hsa - 1234105) 2 xhp-hif1a(胞质)(r - hsa - 1234131) HN-HIF1A(胞质)(r - hsa - 1234110) p-Y565, S797-HIF1A(胞质)(r - hsa - 9634700) p-Y565-HIF1A(胞质)(r - hsa - 8857584) HIF1A(胞质)(r - hsa - 1234102) HIF1A(核浆)(r - hsa - 1234135)	0.564	2
UniProt: MAFG Q9BRP3			0.557	3.
UniProt: Q9UHD8-1 SEPTIN9			0.556	4
UniProt: Q13330 MTA1	2	SUMO2, 3-K509-MTA1(核浆)(r - hsa - 3465537) MTA1(核浆)(r - hsa - 3465550)	0.556	6
UniProt: O60224 SSX4			0.553	2
UniProt: O14818 PSMA7	2	PSMA7(胞质)(r - hsa - 68736) PSMA7(核浆)(r - hsa - 174351)	0.544	2
UniProt: P40818 USP8	2	p-T945-USP8(胞质)(r - hsa - 1358714) USP8(胞质)(r - hsa - 917720)	0.544	2
UniProt: Q8BIF2 RFOX3			0.544	2
UniProt: P51450-2 Rorc	1	Rorc-2(核浆)(r - mmu - 8949302)	0.544	2
UniProt: Q92831 KAT2B	1	KAT2B(核浆)(r - hsa - 352430)	0.524	2
UniProt: Q96CJ1 EAF2	1	EAF2(核浆)(r - hsa - 8932790)	0.524	3.
UniProt: P23771 GATA3	2	PolyUb-GATA3(核浆)(r - hsa - 6783009) GATA3(核浆)(r - hsa - 996768)	0.524	3.
UniProt: P08047 SP1	1	SP1(核浆)(r - hsa - 1592223)	0.524	3.
UniProt: Q5RIX9	1	e2f7(核浆)(r - dre - 6798305)	0.524	2
UniProt: Q9C0J9 BHLHE41	1	BHLHE41(核浆)(r - hsa - 879703)	0.499	2
UniProt: Q99PV5 Bhlhe41	1	Bhlhe41(核浆)(r - mmu - 879802)	0.499	3.
UniProt: Q61539	1	Esrrb(核浆)(r - mmu - 446173)	0.499	2
UniProt: O94888 UBXN7	1	UBXN7(胞质)(r - hsa - 8956071)	0.499	3.
UniProt: P46531 NOTCH1	60	NOTCH1 I1680N S2卵裂片段[细胞外区](r - hsa - 2730744) NOTCH1 L1678P S2卵裂片段[细胞外区](r - hsa - 2730745) NOTCH1 I1718T S2卵裂片段[细胞外区](r - hsa - 2730757) NOTCH1 A1701P S2卵裂片段[质膜](r - hsa - 2730742) NOTCH1 V1676D S2卵裂片段[细胞外区](r - hsa - 2730755) NOTCH1 I1680N跨膜片段[质膜](r - hsa - 2684869) NOTCH1 I1718T跨膜片段[质膜](r - hsa - 2684881) NOTCH1 I1616T胞外片段[胞外区域](r - hsa - 2684866) NOTCH1 L1596H胞外片段[胞外区域](r - hsa - 2684853) 跨膜片段[质膜](r - hsa - 1485591) NOTCH1 A1701P跨膜片段[质膜](r - hsa - 1485585) NOTCH1 I1616N胞外片段[胞外区域](r - hsa - 2684862) 细胞外片段[细胞外区](r - hsa - 1485584) NOTCH1 R1598P细胞外片段[细胞外区](r - hsa - 1485592) NOTCH1 V1576E胞外片段[胞外区域](r - hsa - 2684852) 跨膜片段[质膜](r - hsa - 2684874) NOTCH1 F1592S胞外片段[胞外区域](r - hsa - 2684847) 细胞外片段[细胞外区域](r - hsa - 2691203) p-NICD1 Q2440 (核浆)(r - hsa - 2902207) p-NICD1 Q2395 (核浆)(r - hsa - 2902205) p-NICD1 P2514Rfs * 4(核浆)(r - hsa - 2159809) p-NICD1 P2474Afs * 4(核浆)(r - hsa - 2902204) NOTCH1 L1574P胞外片段[胞外区](r - hsa - 1485582) NOTCH1 L1600P胞外片段[胞外区](r - hsa - 2681764) NEXT1 P2474Afs4[质膜](r - hsa - 2902194) NEXT1 Q2395[质膜](r - hsa - 2902192) NEXT1 Q2440[质膜](r - hsa - 2902196) NEXT1 P2514Rfs4[质膜](r - hsa - 2768989) NICD1 Q2395 (胞质)(r - hsa - 2902195) NICD1 P2514Rfs 4(胞质)(r - hsa - 2768996) NICD1 P2474Afs * 4(胞质)(r - hsa - 2902193) NICD1 Q2440 (胞质)(r - hsa - 2902191) NICD1 P2514Rfs 4(核浆)(r - hsa - 2769013) NICD1 P2474Afs * 4(核浆)(r - hsa - 2902208) NICD1 Q2395 (核浆)(r - hsa - 2902201) NICD1 Q2440 (核浆)(r - hsa - 2902200) P2514Rfs4跨膜片段[质膜](r - hsa - 2768982) NOTCH1 Q2395跨膜片段[质膜](r - hsa - 1485596) NOTCH1 Q2440跨膜片段[质膜](r - hsa - 1485602) NOTCH1 P2474Afs4跨膜片段[质膜](r - hsa - 2894873) NOTCH1 t(7;9)(NOTCH1:M1580_K2555)胞外片段[胞外区](r - hsa - 2220929) p-NICD1(核浆)(r - hsa - 1604444) 相关,GlcNAc-Fuc-Pre-NOTCH1(高尔基体膜)(r - hsa - 1911426) 相关,Gal-GlcNAc-Fuc-Pre-NOTCH1(高尔基体膜)(r - hsa - 1911415) 相关,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH1(高尔基体膜)(r - hsa - 1911503) 边缘修饰的NOTCH1细胞外片段(NECD1)[高尔基膜](r - hsa - 1911511) Pre-NOTCH1[内质网膜](r - hsa - 157024) 17xfect - 2xfics - notch1(19-2555)[内质网膜](r - hsa - 1467396) 19xFucT-14xGlcS-2xFucS-NOTCH1(19-2555)[内质网膜](r - hsa - 1467425) 17 xfuct-14xglcs-2xfucs-notch1(19 - 2555)(高尔基体膜)(r - hsa - 1472872) NOTCH1(1665 - 2555)(高尔基体膜)(r - hsa - 157092) 17 xfuct-14xglcs-2xfucs-notch1(19 - 1664)(高尔基体膜)(r - hsa - 1983679) 边缘修饰的NOTCH1细胞外片段(NECD1)[质膜](r - hsa - 1911512) NOTCH1(1665 - 2555)(质膜)(r - hsa - 157239) 19 xfuct-16xglcs-2xfucs-notch1(19 - 1664)(细胞外地区)(r - hsa - 1983670) NOTCH1(1665 - 1720)(细胞外地区)(r - hsa - 157654) NOTCH1(1721 - 1753)(质膜)(r - hsa - 157656) NEXT1(质膜)(r - hsa - 157200) NICD1(胞质)(r - hsa - 157634) NICD1(核浆)(r - hsa - 157939)	0.499	2
UniProt: P84022 SMAD3	21	p-S423, S425-SMAD3 D258N(胞质)(r - hsa - 3315470) Ub-SMAD3(胞质)(r - hsa - 6782830) p-S423, S425-SMAD3 R268C(胞质)(r - hsa - 3315075) p-S423, S425-SMAD3 R268H(胞质)(r - hsa - 3315080) SMAD3 Q316 (胞质)(r - hsa - 9668765) SMAD3 Y384 (胞质)(r - hsa - 9668782) SMAD3 W326 (胞质)(r - hsa - 9668766) SMAD3 E246 (胞质)(r - hsa - 9668776) SMAD3 Q358 (胞质)(r - hsa - 9668772) SMAD3 Q322 (胞质)(r - hsa - 9668773) SMAD3 S425F(胞质)(r - hsa - 8944158) SMAD3 E383 (胞质)(r - hsa - 9668775) SMAD3 R368 (胞质)(r - hsa - 9668768) SMAD3 Y298 *(胞质)(r - hsa - 9668769) SMAD3 S425C(胞质)(r - hsa - 3308499) 2 xadprib-p-s423 S425-SMAD3(核浆)(r - hsa - 2187326) p-T179、S423 S425-SMAD3(核浆)(r - hsa - 2176471) SMAD3(核浆)(r - hsa - 206150) SMAD3(胞质)(r - hsa - 170855) p-S423, S425-SMAD3(胞质)(r - hsa - 171184) p-S423, S425-SMAD3(核浆)(r - hsa - 177104)	0.463	6
UniProt: P49407 ARRB1	5	PolyUb-ARRB1(胞质)(r - hsa - 6783186) ARRB1(胞质)(r - hsa - 264470) ARRB1(溶酶体膜)(r - hsa - 432701) ARRB1(高尔基体膜)(r - hsa - 350831) 细胞质囊泡膜(r - hsa - 351187)	0.463	3.

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